Search results for " Calprotectin"

showing 5 items of 5 documents

Fecal assays detect hypersensitivity to cow's milk protein and gluten in adults with irritable bowel syndrome.

2011

Background & Aims Some patients with irritable bowel syndrome (IBS)-like symptoms suffer from food hypersensitivity (FH); their symptoms improve when they are placed on elimination diets. No assays identify patients with FH with satisfactory levels of sensitivity. We determined the frequency of FH among patients with symptoms of IBS and the ability of fecal assays for tryptase, eosinophil cationic protein (ECP), or calprotectin to diagnose FH. Methods The study included 160 patients with IBS, 40 patients with other gastrointestinal diseases, and 50 healthy individuals (controls). At the start of the study, patients completed a symptom severity questionnaire, fecal samples were assayed, and …

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaFecal Calprotectin.AdolescentGlutensTryptaseWheat HypersensitivityGastroenterologyIrritable Bowel SyndromePlacebosFecesYoung Adultfluids and secretionsDouble-Blind MethodInternal medicineElimination dietmedicineHumansIrritable bowel syndromeFeceschemistry.chemical_classificationEosinophil cationic proteinHepatologybiologybusiness.industryOral food challengeEosinophil Cationic ProteinGastroenterologyMiddle Agedmedicine.diseaseGlutenDietchemistryGluten SensitivityImmunologybiology.proteinFemaleTryptasesCalprotectinCow’s Milk Protein HypersensitivityMilk HypersensitivitybusinessLeukocyte L1 Antigen ComplexCow’s Milk Protein Hypersensitivity; Gluten Sensitivity; Fecal Tryptase; Fecal Eosinophil Cationic Protein; Fecal Calprotectin.Fecal TryptaseFecal Eosinophil Cationic ProteinClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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Fecal Calprotectin in Self-Reported Milk Intolerance: Not Only Lactose Intolerance

2023

The hypothesis is that inflammatory/allergic conditions should be considered in self-reported milk intolerance (SRMI) patients who test negative and/or are asymptomatic at Lactose Hydrogen Breath Test (LHBT). We analyzed fecal calprotectin (FCP) values in SRMI patients to investigate the frequency of a “positive” intestinal inflammation marker and its correlation with lactose tolerance/intolerance. Data from 329 SRMI patients were retrospectively analyzed; according to the positive/negative results (maldigester/digester) and the presence/absence of symptoms reported during LHBT (intolerant/tolerant), patients were divided into: ‘lactose tolerants’ (n. 104), ‘ma…

cow’s milk proteins allergylactose intolerancelactose hydrogen breath testSettore MED/09 - Medicina InternaNutrition and DieteticsLHBTmilk intoleranceSRMIfecal calprotectinLHBT SRMI cow’s milk proteins allergy fecal calprotectin lactose hydrogen breath test lactose intolerance milk intoleranceFood ScienceNutrients
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Correlation between fecal calprotectin and inflammation in the surgical specimen of Crohn's disease

2016

Background: An accurate assessment of the inflammatory activity is crucial to establish the most appropriate treatment in Crohn's disease (CD). The present study aimed to evaluate the utility of preoperative fecal calprotectin (FC) measurement in small bowel CD and its relationship with inflammatory activity in surgical pathology specimens. Methods: This was a prospective observational study including all the patients with small bowel CD operated on at our center between March 2011 and September 2013. Preoperative laboratory and stool tests were performed. A meticulous exploration of entire small bowel was performed during surgery, and the resected bowel (or a sample of whole intestinal wal…

AdultMalemedicine.medical_specialtyPathologymedicine.medical_treatmentInflammationGastroenterologySensitivity and SpecificitySeverity of Illness IndexSurgical pathology03 medical and health sciencesFeces0302 clinical medicineFecal calprotectinCrohn DiseaseInternal medicineIntestine SmallmedicineStrictureplastyHumansProspective StudiesSurgical pathologyProspective cohort studyAgedAged 80 and overCrohn's diseaseLeukocyte L1 Antigen Complexbusiness.industryBiomarkerMiddle Agedmedicine.diseaseSmall bowel Crohn's disease030220 oncology & carcinogenesisPreoperative PeriodBiomarker (medicine)030211 gastroenterology & hepatologySurgeryFemalemedicine.symptomCalprotectinbusinessLeukocyte L1 Antigen ComplexBiomarkers
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Increased percentages of tumor necrosis factor-alpha+/interferon-gamma+ T lymphocytes and calprotectin+/tumor necrosis factor-alpha+ monocytes in pat…

2012

CalprotectinSettore MED/38 - Pediatria Generale E SpecialisticaKawasaki Disease; Calprotectin; TNF alfaKawasaki DiseaseTNF alfa
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Increased percentages of calprotectin and TNF-Α double-positive monocytes in the acute phase of Kawasaki disease

2011

Background The acute phase of KD is characterized by a deficiency of suppressor T cells, marked activation of the immune system and increased secretion of cytokines by immune effector cells. Moreover, it has been shown that myeloid-related protein (MRP-8 and MRP-14) and S100proteins, the major calcium-binding proteins secreted by activated neutrophils and monocytes, contribute to cause inflammation in acute lesions of KD, and indeed one of the more common hematological alteration in KD is the increase of peripheral blood monocytes. Calprotectin, one of the major calcium-binding proteins, can lead to direct and indirect effects that result not only in inflammation but also in modification of…

Pediatricsmedicine.medical_specialtylcsh:Diseases of the musculoskeletal systemDouble negativeInflammationTNF alfa CalprotectinImmune systemSettore MED/38 - Pediatria Generale E SpecialisticaRheumatologyInternal medicineImmunology and AllergyMedicineSecretionPediatrics Perinatology and Child HealthKawasaki Diseasebusiness.industrylcsh:RJ1-570lcsh:Pediatricsmedicine.diseaseRheumatologyPediatrics Perinatology and Child HealthImmunologyOral PresentationKawasaki diseaselcsh:RC925-935Calprotectinmedicine.symptombusinessVasculitisPediatric Rheumatology Online Journal
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